Blood substitutes. Current status
نویسندگان
چکیده
منابع مشابه
Red blood cell substitutes: current status.
The transfusion of allogeneic blood (or plasma or red cells) involves many hoards (see table 1), some of which may be reduced or avoided. For example, the patient's own blood rather than allogeneic blood may be transfused: by 1990 more than 5% of units collected in the USA were of autologous blood [42]. In the United Kingdom, the National Transfusion Service is now, in some regions at least, pr...
متن کاملPBLD 5: Current Status of Hemoglobin Free Blood Substitutes
CASE #1: 80 year old female with a history of dypsnea on exertion (DOE) and syncope. Workup reveals aortic stenosis (AVA=0.8cm2) and normal coronary arteries by cardiac catheterization with moderate concentric hypertrophy and an EF of 50%. Her other PMH is unremarkable. She was advised by her cardiac surgeon to seek a preoperative anesthetic consultation because she joined the Watch Tower organ...
متن کامل[Hemoglobin-based blood substitutes: current status and perspectives].
BACKGROUND AND OBJECTIVES Alternatives to red blood cells transfusion have been studied since the fifties. This study aimed at presenting current status and perspectives of hemoglobin-based blood substitutes. CONTENTS Potential application areas are presented, in addition to clinical studies involving major hemoglobin molecules developed, their advantages and limitations. CONCLUSIONS Severa...
متن کاملArtificial oxygen carriers as red blood cell substitutes: a selected review and current status.
Two distinct approaches are being explored in red blood cell substitute (RCS) development: hemoglobin-based oxygen carriers (HBOCs) and perfluorocarbon-based oxygen carriers (PFBOCs). HBOCs are based on intra- and/or intermolecularly "engineered" human or animal hemoglobins (Hbs), optimized for O2 delivery and longer intravascular circulation. Some are currently being evaluated in Phase II/III ...
متن کاملBlood substitutes
Blood substitutes have long been sought after, and artificial oxygen carriers may soon become a reality. Despite increased safety of allogeneic blood in terms of transmission of infectious diseases [1], avoiding allogeneic blood transfusions remains an important goal in perioperative and intensive care medicine. This is because allogeneic blood transfusions may cause immunosuppression with an i...
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ژورنال
عنوان ژورنال: Transfusion
سال: 1989
ISSN: 0041-1132,1537-2995
DOI: 10.1046/j.1537-2995.1989.29990070175.x